Comparison of the frequency of functional SH3 domains with different limited sets of amino acids using mRNA display.

Although modern proteins consist of 20 different amino acids, it has been proposed that primordial proteins consisted of a small set of amino acids, and additional amino acids have gradually been recruited into the genetic code. This hypothesis has recently been supported by comparative genome seque...

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Bibliographic Details
Main Authors: Junko Tanaka, Hiroshi Yanagawa, Nobuhide Doi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3061877?pdf=render