Precision Therapy for a Chinese Family With Maturity-Onset Diabetes of the Young

Precision Therapy for a Chinese Family With Maturity-Onset Diabetes of the Young

ObjectiveTo determine the pathogenic gene and explore the clinical characteristics of maturity-onset diabetes of the young type 2 (MODY2) pedigree caused by a mutation in the glucokinase (GCK) gene.MethodsUsing whole-exome sequencing (WES), the pathogenic gene was detected in the proband—a 20-year-o...

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Bibliographic Details
Main Authors: Juyi Li, Meng Shu, Xiufang Wang, Aiping Deng, Chong Wen, Juanjuan Wang, Si Jin, Hongmei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Endocrinology
Subjects:
glucokinase
monogenic diabetes
mutation
MODY2
pedigree
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.700342/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.700342/full

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