Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages

In the brain of patients with multiple sclerosis, activated microglia/macrophages appear in active lesions and in normal appearing white matter. However, whether they play a beneficial or a detrimental role in the development of the pathology remains a controversial issue. The production of pro-infl...

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Bibliographic Details
Main Authors: Tony Valente, Joan Serratosa, Unai Perpiñá, Josep Saura, Carme Solà
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
EAE
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00129/full