Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer

Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer

Tumor progression locus 2 (Tpl2) is a mitogen-activated protein kinase (MAPK) kinase kinase (MAP3K) that conveys various intra- and extra-cellular stimuli to effector proteins of cells provoking adequate adoptive responses. Recent studies have elucidated that Tpl2 is an indispensable signal transduc...

Full description

Bibliographic Details
Main Authors: Hye Won Lee, Han Yong Choi, Kyeung Min Joo, Do-Hyun Nam
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:International Journal of Molecular Sciences
Subjects:
tumor progression locus 2
cot
mitogen-activated protein kinase kinase kinase 8
cancer
oncogene
tumor suppressor gene
therapeutic target
Online Access:http://www.mdpi.com/1422-0067/16/3/4471

Internet

http://www.mdpi.com/1422-0067/16/3/4471

Similar Items