Interaction of selected platinum(II) complexes containing roscovitine-based CDK inhibitors as ligands with human liver microsomal cytochrome P450

Interaction of selected platinum(II) complexes containing roscovitine-based CDK inhibitors as ligands with human liver microsomal cytochrome P450

Background: We studied the interaction of oxaliplatin derivatives involving cytotoxic adenine-based cyclin-dependent kinase inhibitors, with human liver microsomal cytochrome P450. Methods and Results: The activities of 9 human liver microsomal CYP forms (CYPs 1A2, 7-ethoxyresorufin O-deethylation;...

Full description

Bibliographic Details
Main Authors: Vlastimil Masek, Pavel Starha, Monika Harvanova, Martina Michalova, David Milde, Zdenek Travnicek, Eva Anzenbacherova
Format: Article
Language:English
Published: Palacký University Olomouc, Faculty of Medicine and Dentistry 2015-09-01
Series:Biomedical Papers
Subjects:
cytochrome p450
platinum(ii) complexes
cdk inhibition
roscovitine derivatives
Online Access:https://biomed.papers.upol.cz/artkey/bio-201503-0008_Interaction_of_selected_platinum_II_complexes_containing_roscovitine-based_CDK_inhibitors_as_ligands_with_huma.php

Internet

https://biomed.papers.upol.cz/artkey/bio-201503-0008_Interaction_of_selected_platinum_II_complexes_containing_roscovitine-based_CDK_inhibitors_as_ligands_with_huma.php

Similar Items