Efficient Production of Chimeric Hepatitis B Virus-Like Particles Bearing an Epitope of Hepatitis E Virus Capsid by Transient Expression in <i>Nicotiana benthamiana</i>

The core antigen of hepatitis B virus (HBcAg) is capable of self-assembly into virus-like particles (VLPs) when expressed in a number of heterologous systems. Such VLPs are potential carriers of foreign antigenic sequences for vaccine design. In this study, we evaluated the production of chimeric HB...

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Bibliographic Details
Main Authors: Gergana Zahmanova, Milena Mazalovska, Katerina Takova, Valentina Toneva, Ivan Minkov, Hadrien Peyret, George Lomonossoff
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/1/64