<i>N</i>-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

<i>N</i>-Palmitoylethanolamide-Oxazoline Protects against Middle Cerebral Artery Occlusion Injury in Diabetic Rats by Regulating the SIRT1 Pathway

Diabetes causes various macrovascular and microvascular alterations, often culminating in major clinical complications (first of all, stroke) that lack an effective therapeutic intervention. <i>N</i>-palmitoylethanolamide-oxazoline (PEA-OXA) possesses anti-inflammatory and potent neuropr...

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Bibliographic Details
Main Authors: Roberta Fusco, Maria Scuto, Marika Cordaro, Ramona D’Amico, Enrico Gugliandolo, Rosalba Siracusa, Alessio Filippo Peritore, Rosalia Crupi, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
ischemic stroke
pea-oxa
inflammation
Online Access:https://www.mdpi.com/1422-0067/20/19/4845

Internet

https://www.mdpi.com/1422-0067/20/19/4845

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