Gene networks and expression quantitative trait loci associated with adjuvant chemotherapy response in high-grade serous ovarian cancer

Gene networks and expression quantitative trait loci associated with adjuvant chemotherapy response in high-grade serous ovarian cancer

Abstract Background A major impediment in the treatment of ovarian cancer is the relapse of chemotherapy-resistant tumors, which occurs in approximately 25% of patients. A better understanding of the biological mechanisms underlying chemotherapy resistance will improve treatment efficacy through gen...

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Bibliographic Details
Main Authors: Jihoon Choi, Danai G. Topouza, Anastasiya Tarnouskaya, Sean Nesdoly, Madhuri Koti, Qing Ling Duan
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Chemotherapy resistance
Co-expression network analysis
Valosin containing protein
Expression quantitative trait loci
The Cancer Genome Atlas
High-grade serous ovarian carcinoma
Online Access:http://link.springer.com/article/10.1186/s12885-020-06922-1

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http://link.springer.com/article/10.1186/s12885-020-06922-1

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