Trypanosome lytic factor, an antimicrobial high-density lipoprotein, ameliorates Leishmania infection.

Innate immunity is the first line of defense against invading microorganisms. Trypanosome Lytic Factor (TLF) is a minor sub-fraction of human high-density lipoprotein that provides innate immunity by completely protecting humans from infection by most species of African trypanosomes, which belong to...

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Bibliographic Details
Main Authors: Marie Samanovic, Maria Pilar Molina-Portela, Anne-Danielle C Chessler, Barbara A Burleigh, Jayne Raper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2622765?pdf=render