Neuronal Nitric Oxide Synthase Induction in the Antitumorigenic and Neurotoxic Effects of 2-Methoxyestradiol

Neuronal Nitric Oxide Synthase Induction in the Antitumorigenic and Neurotoxic Effects of 2-Methoxyestradiol

Objective: 2-Methoxyestradiol, one of the natural 17β-estradiol derivatives, is a novel, potent anticancer agent currently being evaluated in advanced phases of clinical trials. The main goal of the study was to investigate the anticancer activity of 2-methoxy-estradiol towards osteosarcoma cells...

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Bibliographic Details
Main Authors: Magdalena Gorska, Alicja Kuban-Jankowska, Michal Aleksander Zmijewski, Monika Gorzynik, Michal Szkatula, Michal Wozniak
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Molecules
Subjects:
osteosarcoma
hippocampus
cancer
neurodegenerative disease
2-methoxyestradiol
neuronal nitric oxide synthase
3-nitrotyrosine
Online Access:http://www.mdpi.com/1420-3049/19/9/13267

Internet

http://www.mdpi.com/1420-3049/19/9/13267

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