Erythropoietin protects sensory axons against paclitaxel-induced distal degeneration

Paclitaxel causes a sensory polyneuropathy with characteristic features of distal axonal degeneration. Although the exact mechanisms underlying distal axonal degeneration are unknown, paclitaxel-induced axonal degeneration has been shown to be associated with an increase in detyrosinated tubulin. He...

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Bibliographic Details
Main Authors: Giorgia Melli, Christelene Jack, George L. Lambrinos, Mathias Ringkamp, Ahmet Höke
Format: Article
Language:English
Published: Elsevier 2006-12-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106002087