CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota

Summary: Interleukin-17-producing γδ T (γδ17) cells play a central role in protective and pathogenic immune responses. However, the tissue-specific mechanisms that control the activation of these innate lymphocytes are not known. Here, we demonstrate that CD109, a glycosylphosphatidylinositol (GPI)-...

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Bibliographic Details
Main Authors: Hualin Zhang, Giustino Carnevale, Barbara Polese, Melissa Simard, Bavanitha Thurairajah, Nargis Khan, Maria E. Gentile, Ghislaine Fontes, Donald C. Vinh, Roxane Pouliot, Irah L. King
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719311714