Efficient whole-cell oxidation of α,β-unsaturated alcohols to α,β-unsaturated aldehydes through the cascade biocatalysis of alcohol dehydrogenase, NADPH oxidase and hemoglobin

Efficient whole-cell oxidation of α,β-unsaturated alcohols to α,β-unsaturated aldehydes through the cascade biocatalysis of alcohol dehydrogenase, NADPH oxidase and hemoglobin

Abstract Background α,β-Unsaturated aldehydes are widely used in the organic synthesis of fine chemicals for application in products such as flavoring agents, fragrances and pharmaceuticals. In the selective oxidation of α,β-unsaturated alcohols to the corresponding α,β-unsaturated aldehydes, it rem...

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Bibliographic Details
Main Authors: Yan Qiao, Can Wang, Yin Zeng, Tairan Wang, Jingjing Qiao, Chenze Lu, Zhao Wang, Xiangxian Ying
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Microbial Cell Factories
Subjects:
α,β-Unsaturated aldehydes
Alcohol dehydrogenase
NADPH oxidase
NADP+ regeneration
Enzyme fusion
Online Access:https://doi.org/10.1186/s12934-021-01511-8

Internet

https://doi.org/10.1186/s12934-021-01511-8

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