Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.

Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.

Molecular, cellular, and clinical studies have combined to demonstrate a contribution from the DNA cytosine deaminase APOBEC3B (A3B) to the overall mutation load in breast, head/neck, lung, bladder, cervical, ovarian, and other cancer types. However, the complete landscape of mutations attributable...

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Bibliographic Details
Main Authors: Monica K Akre, Gabriel J Starrett, Jelmar S Quist, Nuri A Temiz, Michael A Carpenter, Andrew N J Tutt, Anita Grigoriadis, Reuben S Harris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4862684?pdf=render

Internet

http://europepmc.org/articles/PMC4862684?pdf=render

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