Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.

Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.

Lung cancer is the most common malignancy and the leading cause of cancer deaths worldwide. While smoking is by far the leading cause of lung cancer, other environmental and genetic factors influence the development and progression of the cancer. Since unique mutations patterns have been observed in...

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Bibliographic Details
Main Authors: Xin Cai, Jianhui Sheng, Chuanning Tang, Vijayalakshmi Nandakumar, Hua Ye, Hong Ji, Haiying Tang, Yu Qin, Hongwei Guan, Feng Lou, Dandan Zhang, Hong Sun, Haichao Dong, Guangchun Zhang, Zhiyuan Liu, Zhishou Dong, Baishuai Guo, He Yan, Chaowei Yan, Lu Wang, Ziyi Su, Yangyang Li, Lindsey Jones, Xue F Huang, Si-Yi Chen, Taihua Wu, Hongli Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3997391?pdf=render

Internet

http://europepmc.org/articles/PMC3997391?pdf=render

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