Rac1 modification by an electrophilic 15-deoxy Δ12,14-prostaglandin J2 analog

Rac1 modification by an electrophilic 15-deoxy Δ12,14-prostaglandin J2 analog

Vascular endothelial cells (ECs) are important for maintaining vascular homeostasis. Dysfunction of ECs contributes to cardiovascular diseases, including atherosclerosis, and can impair the healing process during vascular injury. An important mediator of EC response to stress is the GTPase Rac1. Ra...

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Bibliographic Details
Main Authors: S.B. Wall, J.-Y. Oh, L. Mitchell, A.H. Laube, S.L. Campbell, M.B. Renfrow, A. Landar
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Redox Biology
Subjects:
Cyclopentenone
Electrophile responsive proteome
Oxidative post-translational modification
Redox signaling
Rho GTPase
Thiol
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171500018X

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http://www.sciencedirect.com/science/article/pii/S221323171500018X

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