Hypoxia and Angiogenesis in Endometrioid Endometrial Carcinogenesis

Background: Hypoxia-inducible factor 1α (HIF-1α) plays an essential role in the adaptive response of cells to hypoxia, triggering biologic events associated with aggressive tumor behavior. Methods: Expression of HIF-1α and proteins in the HIF-1α pathway (Glut-1, CAIX, VEGF) in paraffin-embedded spec...

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Bibliographic Details
Main Authors: Nicole Horrée, Paul J. van Diest, Petra van der Groep, Daisy M. D. S. Sie-Go, A. Peter M. Heintz
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.1155/2007/434731