BLOCKADE OF ROSTRAL VENTROLATERAL MEDULLA (RVLM) BOMBESIN RECEPTOR TYPE 1 DECREASES BLOOD PRESSURE AND SYMPATHETIC ACTIVITY IN ANESTHETIZED SPONTANEOUSLY HYPERTENSIVE RATS

BLOCKADE OF ROSTRAL VENTROLATERAL MEDULLA (RVLM) BOMBESIN RECEPTOR TYPE 1 DECREASES BLOOD PRESSURE AND SYMPATHETIC ACTIVITY IN ANESTHETIZED SPONTANEOUSLY HYPERTENSIVE RATS

IIntrathecal injection of bombesin (BBS) promoted hypertensive and sympathoexcitatory effects in normotensive (NT) rats. However, the involvement of rostral ventrolateral medulla (RVLM) in these responses is still unclear. In the present study, we investigated: (1) the effects of BBS injected bilate...

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Bibliographic Details
Main Authors: Izabella Silva De Jesus Pinto, Aline Andrade Mourão, Elaine Fernanda da Silva, Amanda Sales Camargo, Stefanne Madalena Marques, Karina Pereira Gomes, James Oluwagbamigbe Fajemiroye, Angela Adamski da Silva Reis, Ana Cristina Silva Rebelo, Marcos L. Ferreira-Neto, Daniel Alves Rosa, André Henrique Freiria-Oliveira, Carlos Henrique de Castro, Eduardo eColombari, Diego Basile Colugnati, Gustavo Rodrigues Pedrino
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Physiology
Subjects:
Bombesin
SHR
rostral ventrolateral medulla
BB1 receptors
BIM-23127
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00205/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00205/full

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