Subclassification of newly diagnosed glioblastomas through an immunohistochemical approach.

Molecular signatures in Glioblastoma (GBM) have been described that correlate with clinical outcome and response to therapy. The Proneural (PN) and Mesenchymal (MES) signatures have been identified most consistently, but others including Classical (CLAS) have also been reported. The molecular signat...

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Bibliographic Details
Main Authors: Siobhan Conroy, Frank A E Kruyt, Justin V Joseph, Veerakumar Balasubramaniyan, Krishna P Bhat, Michiel Wagemakers, Roelien H Enting, Annemiek M E Walenkamp, Wilfred F A den Dunnen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0115687