Non-muscle myosin II in disease: mechanisms and therapeutic opportunities

The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell morphology, with a role in several essential cellular processes, including cell migration and post-synaptic dendritic spine plasticity in neurons. NMII also generates forces that alter biochemical signaling, by dr...

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Bibliographic Details
Main Authors: Karen A. Newell-Litwa, Rick Horwitz, Marcelo L. Lamers
Format: Article
Language:English
Published: The Company of Biologists 2015-12-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/8/12/1495