Non-muscle myosin II in disease: mechanisms and therapeutic opportunities
The actin motor protein non-muscle myosin II (NMII) acts as a master regulator of cell morphology, with a role in several essential cellular processes, including cell migration and post-synaptic dendritic spine plasticity in neurons. NMII also generates forces that alter biochemical signaling, by dr...
Main Authors: | Karen A. Newell-Litwa, Rick Horwitz, Marcelo L. Lamers |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-12-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/8/12/1495 |
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