A randomized open label trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis. [version 1; referees: 2 approved]

A randomized open label trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis. [version 1; referees: 2 approved]

Background: Cryptococcal meningitis is a leading cause of death in HIV-infected patients. International treatment guidelines recommend induction therapy with amphotericin B and flucytosine. This antifungal combination is most effective, but unfortunately flucytosine is expensive and unavailable wher...

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Bibliographic Details
Main Authors: Nguyen Thi Thuy Ngan, Nguyen Thi Hoang Mai, Nguyen Le Nhu Tung, Nguyen Phu Huong Lan, Luong Thi Hue Tai, Nguyen Hoan Phu, Nguyen Van Vinh Chau, Tran Quang Binh, Le Quoc Hung, Justin Beardsley, Nicholas White, David Lalloo, Damian Krysan, William Hope, Ronald Geskus, Marcel Wolbers, Le Thanh Hoang Nhat, Guy Thwaites, Evelyne Kestelyn, Jeremy Day
Format: Article
Language:English
Published: Wellcome 2019-01-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/4-8/v1

Internet

https://wellcomeopenresearch.org/articles/4-8/v1

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