RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis

T-cells are known to be intimately involved in the pathogenesis of multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE). T-cell activation is controlled by a range of intracellular signaling pathways regulating cellular responses such as proliferation, cytokin...

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Bibliographic Details
Main Authors: Alba Manresa-Arraut, Flemming Fryd Johansen, Cord Brakebusch, Shohreh Issazadeh-Navikas, Henrik Hasseldam
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Immunology
Subjects:
RhoA
multiple sclerosis
experimental autoimmune encephalomyelitis
T-cell
neuroinflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01235/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01235/full

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