Alpha glucosidase inhibition activity of phenolic fraction from Simarouba glauca: An in-vitro, in-silico and kinetic study

A phenolic rich fraction purified from Simarouba glauca leaves was effective in alpha glucosidase inhibition. The purified fraction named ‘fraction-14’ had shown significant inhibition of yeast alpha glucosidase enzyme activity (IC50 = 2.4 ± 0.4 μg/mL) when compared to anti-diabetic drug acarbose (I...

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Bibliographic Details
Main Authors: Kirana P. Mugaranja, Ananda Kulal
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020312366