Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection

Enhanced expression of immune checkpoint receptors during SARS-CoV-2 viral infection

The immune system is tightly regulated by the activity of stimulatory and inhibitory immune receptors. This immune homeostasis is usually disturbed during chronic viral infection. Using publicly available transcriptomic datasets, we conducted in silico analyses to evaluate the expression pattern of...

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Bibliographic Details
Main Authors: Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Bushra Mdkhana, Saba Al Heialy, Habiba S. Alsafar, Rifat Hamoudi, Qutayba Hamid, Rabih Halwani
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
SARS-CoV-2
COVID-19
immune inhibitory receptors
immune checkpoint inhibitors
CEACAM1
SIGLEC10
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120302291

Internet

http://www.sciencedirect.com/science/article/pii/S2329050120302291

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