Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease

Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease

Background: Neuroimaging shows considerable promise in generating sensitive and objective outcome measures for therapeutic trials across a range of neurodegenerative conditions. For volumetric measures the current gold standard is manual delineation, which is unfeasible for samples sizes required fo...

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Bibliographic Details
Main Authors: Nina M. Mansoor, Tishok Vanniyasingam, Ian Malone, Nicola Z. Hobbs, Elin Rees, Alexandra Durr, Raymund A. C. Roos, Bernhard Landwehrmeyer, Sarah J. Tabrizi, Eileanoir B. Johnson, Rachael I. Scahill
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neurology
Subjects:
caudate
automated segmentation
Huntington (disease)
FreeSurfer
FIRST
STEPS
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.616272/full

Internet

https://www.frontiersin.org/articles/10.3389/fneur.2021.616272/full

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