Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

Direct neuronal reprogramming, by which a neuron is formed via direct conversion from a somatic cell without going through a pluripotent intermediate stage, allows for the possibility of generating patient-derived neurons. A unique feature of these so-called induced neurons (iNs) is the potential to...

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Bibliographic Details
Main Authors: Janelle Drouin-Ouellet, Karolina Pircs, Roger A. Barker, Johan Jakobsson, Malin Parmar
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Neuroscience
Subjects:
induced neurons
direct neural reprogramming
disease modeling
neurological disorders
neurodegenerative diseases
Online Access:http://journal.frontiersin.org/article/10.3389/fnins.2017.00530/full

Internet

http://journal.frontiersin.org/article/10.3389/fnins.2017.00530/full

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