Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors

Variability in German Cockroach Extract Composition Greatly Impacts T Cell Potency in Cockroach-Allergic Donors

German cockroach extract is used clinically to evaluate allergen-specific sensitization and for subcutaneous allergen-specific immunotherapy, though there are no guidelines for standardization in its manufacture. We performed an immunological evaluation of 12 different cockroach extracts prepared fr...

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Bibliographic Details
Main Authors: Giovanni Birrueta, April Frazier, Anna Pomés, Jill Glesner, Stephanie Filep, Coby Schal, Kyoung Yong Jeong, Curtis McMurtrey, Thomas Vander Schans, William H. Hildebrand, Paula Busse, Avraham Beigelman, Leonard B. Bacharier, Bjoern Peters, Alessandro Sette, Véronique Schulten
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
German cockroach
T cells
allergen extract
cytokines
respiratory allergy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00313/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00313/full

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