Immunomodulatory effects of bone marrow-derived mesenchymal stem cells in a swine hemi-facial allotransplantation model.

BACKGROUND: In this study, we investigated whether the infusion of bone marrow-derived mesenchymal stem cells (MSCs), combined with transient immunosuppressant treatment, could suppress allograft rejection and modulate T-cell regulation in a swine orthotopic hemi-facial composite tissue allotranspla...

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Bibliographic Details
Main Authors: Yur-Ren Kuo, Chien-Chang Chen, Shigeru Goto, Yu-Ting Huang, Chun-Ting Wang, Chia-Chun Tsai, Chao-Long Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338845?pdf=render