Inhibition of CYR61-S100A4 Axis Limits Breast Cancer Invasion

Background and Objective: Matricellular proteins modulate the micro environment of tumors and are recognized to contribute to tumor cell invasion and dissemination. The cysteine-rich angiogenic inducer 61 (CYR61) is upregulated in mesenchymal transformed and invasive breast cancer cells. CYR61 corre...

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Bibliographic Details
Main Authors: Johanna W. Hellinger, Silke Hüchel, Lena Goetz, Gerd Bauerschmitz, Günter Emons, Carsten Gründker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Oncology
Subjects:
EMT
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01074/full