Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

Summary Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects. Gastrulation is a particularly sensitive developmental stage for teratogen exposure,...

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Bibliographic Details
Main Authors: Swapnalee Sarmah, Pooja Muralidharan, Courtney L. Curtis, Jeanette N. McClintick, Bryce B. Buente, David J. Holdgrafer, Osato Ogbeifun, Opeyemi C. Olorungbounmi, Liliana Patino, Ryan Lucas, Sonya Gilbert, Evan S. Groninger, Julia Arciero, Howard J. Edenberg, James A. Marrs
Format: Article
Language:English
Published: The Company of Biologists 2013-08-01
Series:Biology Open
Subjects:
Fetal alcohol spectrum disorder
Gastrulation
Cell adhesion
Zebrafish
Online Access:http://bio.biologists.org/content/2/10/1013

Internet

http://bio.biologists.org/content/2/10/1013

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