Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake

Elabela Protects Spontaneously Hypertensive Rats From Hypertension and Cardiorenal Dysfunctions Exacerbated by Dietary High-Salt Intake

Objectives: Arterial hypertension, when exacerbated by excessive dietary salt intake, worsens the morbidity and mortality rates associated with cardiovascular and renal diseases. Stimulation of the apelinergic system appears to protect against several circulatory system diseases, but it remains unkn...

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Bibliographic Details
Main Authors: Xavier Sainsily, David Coquerel, Hugo Giguère, Lauralyne Dumont, Kien Tran, Christophe Noll, Andrei L. Ionescu, Jérôme Côté, Jean-Michel Longpré, André Carpentier, Éric Marsault, Olivier Lesur, Philippe Sarret, Mannix Auger-Messier
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
Elabela/Toddler
Apelin
APJ receptor
ACE2
neprilysin
hypertension
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.709467/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.709467/full

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