Retinal blood flow dysregulation precedes neural retinal dysfunction in type 2 diabetic mice

Abstract We investigated and compared the susceptibility of retinal blood flow regulation and neural function in mice developing type 2 diabetes. The longitudinal changes in retinal neuronal function and blood flow responses to a 10-min systemic hyperoxia and a 3-min flicker stimulation were evaluat...

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Bibliographic Details
Main Authors: Junya Hanaguri, Harumasa Yokota, Masahisa Watanabe, Satoru Yamagami, Akifumi Kushiyama, Lih Kuo, Taiji Nagaoka
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97651-3