Characterizing low dose and dose rate effects in rodent and human neural stem cells exposed to proton and gamma irradiation

Characterizing low dose and dose rate effects in rodent and human neural stem cells exposed to proton and gamma irradiation

Past work has shown that exposure to gamma rays and protons elicit a persistent oxidative stress in rodent and human neural stem cells (hNSCs). We have now adapted these studies to more realistic exposure scenarios in space, using lower doses and dose rates of these radiation modalities, to further...

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Bibliographic Details
Main Authors: Bertrand P. Tseng, Mary L. Lan, Katherine K. Tran, Munjal M. Acharya, Erich Giedzinski, Charles L. Limoli
Format: Article
Language:English
Published: Elsevier 2013-01-01
Series:Redox Biology
Subjects:
Neural stem cells
Protons
Dose rate
Radiation
DNA damage
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231713000293

Internet

http://www.sciencedirect.com/science/article/pii/S2213231713000293

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