Metastatic pathway and the microvascular and physicochemical microenvironments of human melanoma xenografts

Abstract Background Malignant melanoma of the skin can metastasize through blood vessels and lymphatics. The primary tumor develops a vascular microenvironment characterized by abnormal blood vessels and lymphatics and a physicochemical microenvironment characterized by low oxygen tension, regions w...

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Bibliographic Details
Main Authors: Ruixia Huang, Lise Mari K. Andersen, Einar K. Rofstad
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Translational Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12967-017-1307-4