Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement

Accelerated 19F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement

Paramagnetic gadolinium ions (GdIII), complexed within DOTA-based chelates, have become useful tools to increase the magnetic resonance imaging (MRI) contrast in tissues of interest. Recently, “on/off” probes serving as 19F·MRI biosensors for target enzymes have emerged that utilize the increase in...

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Bibliographic Details
Main Authors: Henryk M. Faas, James L. Krupa, Alexander J. Taylor, Francesco Zamberlan, Christopher J. Philp, Huw E. L. Williams, Simon R. Johnson, Galina E. Pavlovskaya, Neil R. Thomas, Thomas Meersmann
Format: Article
Language:English
Published: Hindawi-Wiley 2019-01-01
Series:Contrast Media & Molecular Imaging
Online Access:http://dx.doi.org/10.1155/2019/4826520

Internet

http://dx.doi.org/10.1155/2019/4826520

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