Biomarker evidence of axonal injury in neuroasymptomatic HIV-1 patients.

Prevalence of neurocognitive impairment in HIV-1 infected patients is reported to be high. Whether this is a result of active HIV-related neurodegeneration is unclear. We examined axonal injury in HIV-1 patients by measuring the light subunit of neurofilament protein (NFL) in CSF with a novel, sensi...

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Bibliographic Details
Main Authors: Jan Jessen Krut, Tomas Mellberg, Richard W Price, Lars Hagberg, Dietmar Fuchs, Lars Rosengren, Staffan Nilsson, Henrik Zetterberg, Magnus Gisslén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3921217?pdf=render