Treatment of Rheumatoid Arthritis Using Combination of Methotrexate and Tripterygium Glycosides Tablets—A Quantitative Plasma Pharmacochemical and Pseudotargeted Metabolomic Approach

Treatment of Rheumatoid Arthritis Using Combination of Methotrexate and Tripterygium Glycosides Tablets—A Quantitative Plasma Pharmacochemical and Pseudotargeted Metabolomic Approach

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by chronic destructive synovitis and is associated with progressive disability, systemic difficulties, premature death, and socioeconomic costs. Early intervention with disease-modifying antirheumatic drugs (DMARDs) like metho...

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Bibliographic Details
Main Authors: Menglei Wang, Jing Huang, Huizhen Fan, Dan He, Siyu Zhao, Yisong Shu, Hui Li, Linlin Liu, Shuang Lu, Cheng Xiao, Yuanyan Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
methotrexate
tripterygium glycosides tablets
combination treatment
quantitative plasma pharmacochemistry
pseudotargeted metabolomics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01051/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01051/full

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