Impact of sequencing depth and technology on de novo RNA-Seq assembly

Impact of sequencing depth and technology on de novo RNA-Seq assembly

Abstract Background RNA-Seq data is inherently nonuniform for different transcripts because of differences in gene expression. This makes it challenging to decide how much data should be generated from each sample. How much should one spend to recover the less expressed transcripts? The sequencing t...

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Bibliographic Details
Main Authors: Jordan Patterson, Eric J. Carpenter, Zhenzhen Zhu, Dan An, Xinming Liang, Chunyu Geng, Radoje Drmanac, Gane Ka-Shu Wong
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Genomics
Subjects:
Rna-seq assembly
Sequencing depth
Sequencing technology
Online Access:http://link.springer.com/article/10.1186/s12864-019-5965-x

Internet

http://link.springer.com/article/10.1186/s12864-019-5965-x

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