Altered Secretome and ROS Production in Olfactory Mucosa Stem Cells Derived from Friedreich’s Ataxia Patients

Altered Secretome and ROS Production in Olfactory Mucosa Stem Cells Derived from Friedreich’s Ataxia Patients

Friedreich’s ataxia is the most common hereditary ataxia for which there is no cure or approved treatment at present. However, therapeutic developments based on the understanding of pathological mechanisms underlying the disease have advanced considerably, with the implementation of cellular models...

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Bibliographic Details
Main Authors: Sara Pérez-Luz, Frida Loria, Yurika Katsu-Jiménez, Daniel Oberdoerfer, Oscar-Li Yang, Filip Lim, José Luis Muñoz-Blanco, Javier Díaz-Nido
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
Frataxin
Friedreich´s ataxia
gene therapy
stem cells human olfactory mucosa
Online Access:https://www.mdpi.com/1422-0067/21/18/6662

Internet

https://www.mdpi.com/1422-0067/21/18/6662

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