Validating the Paradigm That Biomechanical Forces Regulate Embryonic Cardiovascular Morphogenesis and Are Fundamental in the Etiology of Congenital Heart Disease

The goal of this review is to provide a broad overview of the biomechanical maturation and regulation of vertebrate cardiovascular (CV) morphogenesis and the evidence for mechanistic relationships between function and form relevant to the origins of congenital heart disease (CHD). The embryonic hear...

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Bibliographic Details
Main Authors: Bradley B. Keller, William J. Kowalski, Joseph P. Tinney, Kimimasa Tobita, Norman Hu
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/7/2/23