Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model.

Desensitization and treatment with APRIL/BLyS blockade in rodent kidney transplant model.

Alloantibody represents a significant barrier in kidney transplant through the sensitization of patients prior to transplant through antibody mediated rejection (ABMR). APRIL BLyS are critical survival factors for mature B lymphocytes plasma cells, the primary source of alloantibody. We examined the...

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Bibliographic Details
Main Authors: Natalie M Bath, Xiang Ding, Nancy A Wilson, Bret M Verhoven, Brittney A Boldt, Adarsh Sukhwal, Shannon R Reese, Sarah E Panzer, Arjang Djamali, Robert R Redfield
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211865

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https://doi.org/10.1371/journal.pone.0211865

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