Mitochondrial oxidative stress causes hyperphosphorylation of tau.
Age-related neurodegenerative disease has been mechanistically linked with mitochondrial dysfunction via damage from reactive oxygen species produced within the cell. We determined whether increased mitochondrial oxidative stress could modulate or regulate two of the key neurochemical hallmarks of A...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1888726?pdf=render |