Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers.

Formalin-inactivated EV71 vaccine candidate induced cross-neutralizing antibody against subgenotypes B1, B4, B5 and C4A in adult volunteers.

<h4>Background</h4>Enterovirus 71 (EV71) has caused several epidemics of hand, foot and mouth diseases (HFMD) in Asia. No effective EV71 vaccine is available. A randomized and open-label phase I clinical study registered with ClinicalTrials.gov #NCT01268787, aims to evaluate the safety,...

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Bibliographic Details
Main Authors: Ai-Hsiang Chou, Chia-Chyi Liu, Jui-Yuan Chang, Renee Jiang, Yi-Chin Hsieh, Amanda Tsao, Chien-Long Wu, Ju-Lan Huang, Chang-Phone Fung, Szu-Min Hsieh, Ya-Fang Wang, Jen-Ren Wang, Mei-Hua Hu, Jen-Ron Chiang, Ih-Jen Su, Pele Choi-Sing Chong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24278177/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24278177/?tool=EBI

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