Mass Spectrometry-Based Proteomics for the Analysis of Chromatin Structure and Dynamics

Mass Spectrometry-Based Proteomics for the Analysis of Chromatin Structure and Dynamics

Chromatin is a highly structured nucleoprotein complex made of histone proteins and DNA that controls nearly all DNA-dependent processes. Chromatin plasticity is regulated by different associated proteins, post-translational modifications on histones (hPTMs) and DNA methylation, which act in a conce...

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Bibliographic Details
Main Authors: Monica Soldi, Alessandro Cuomo, Michael Bremang, Tiziana Bonaldi
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:International Journal of Molecular Sciences
Subjects:
chromatin
histone post-translational modifications (hPTMs)
combinatorial modifications
epigenetics
mass spectrometry
proteomics
SILAC
histone code readers
histone variants
Online Access:http://www.mdpi.com/1422-0067/14/3/5402

Internet

http://www.mdpi.com/1422-0067/14/3/5402

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