Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

Background: Penicillin G, the current standard treatment for syphilis, has important drawbacks, but virtually no preclinical or clinical studies have been performed to identify viable alternatives. We tested, both in vitro and in vivo, three marketed antibiotics with adequate pharmacological propert...

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Bibliographic Details
Main Authors: Austin M. Haynes, Lorenzo Giacani, Marti Vall Mayans, Maria Ubals, Carles Nieto, Clara Pérez-Mañá, Llorenç Quintó, Emily Romeis, Oriol Mitjà
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EBioMedicine
Subjects:
Treponema pallidum
Syphilis
Yaws
Repurposing
Linezolid
Preclinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000748

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http://www.sciencedirect.com/science/article/pii/S2352396421000748

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