Allele-Specific MicroRNA-Mediated Regulation of a Glycolysis Gatekeeper PDK1 in Cancer Metabolism
Background: Emerging evidence has revealed that genetic variations in microRNA (miRNA) binding sites called miRSNPs can alter miRNA binding in an allele-specific manner and impart prostate cancer (PCa) risk. Two miRSNPs, rs1530865 (G > C) and rs2357637 (C > A), in the 3′ untranslated region of...
Main Authors: | Sugarniya Subramaniam, Varinder Jeet, Jennifer H. Gunter, Judith A. Clements, Jyotsna Batra |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/13/14/3582 |
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