Synergistic anti-proliferative effects of combination of ABT-263 and MCL-1 selective inhibitor A-1210477 on cervical cancer cell lines

Abstract Objective There are number of studies which report that BCL-2 anti-apoptotic proteins (e.g. BCL-2, BCL-XL, and MCL-1) are highly expressed in cervical cancer tissues compared to the normal cervical epithelia. Despite these reports, targeting these proteins for cervical cancer treatment has...

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Bibliographic Details
Main Authors: Benedict Shi Xiang Lian, Angeline En Hui Yek, Hemalata Shuvas, Siti Fairus Abdul Rahman, Kalaivani Muniandy, Nethia Mohana-Kumaran
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-018-3302-0