Synthesis and immunological evaluation of protein conjugates of Neisseria meningitidis X capsular polysaccharide fragments

Synthesis and immunological evaluation of protein conjugates of Neisseria meningitidis X capsular polysaccharide fragments

A vaccine to prevent infections from the emerging Neisseria meningitidis X (MenX) is becoming an urgent issue. Recently MenX capsular polysaccharide (CPS) fragments conjugated to CRM197 as carrier protein have been confirmed at preclinical stage as promising candidates for vaccine development. Howev...

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Bibliographic Details
Main Authors: Laura Morelli, Damiano Cancogni, Marta Tontini, Alberto Nilo, Sara Filippini, Paolo Costantino, Maria Rosaria Romano, Francesco Berti, Roberto Adamo, Luigi Lay
Format: Article
Language:English
Published: Beilstein-Institut 2014-10-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
carbohydrates
glycoconjugates
immunology
multivalent glycosystems Neisseria meningitidis
vaccines
Online Access:https://doi.org/10.3762/bjoc.10.247

Internet

https://doi.org/10.3762/bjoc.10.247

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