Notch signaling-mediated osteocytic overexpression of BMP4 promotes osteogenic differentiation of bone marrow stromal cells

Objective To investigate the effect of bone morphogenetic protein 4 (BMP4) overexpression in MLO-Y4 osteocytes on osteogenic differentiation of bone marrow stromal ST2 cells through Notch signaling. Methods Ad-GFP or Ad-BMP4 infected MLO-Y4 cells were co-cultured with ST2 cells, and designated as GF...

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Bibliographic Details
Main Authors: XIE Zhengsong, ZHAO Yixin, LYU Ziling, LIU Hong, TU Xiaolin
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-08-01
Series:Di-san junyi daxue xuebao
Subjects:
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202102063.htm